Claudin Proteins in Ovarian Cancer
Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2007-01-01
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| Series: | Disease Markers |
| Online Access: | http://dx.doi.org/10.1155/2007/674058 |
| Summary: | Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets for therapy using the Clostridium perfringens enterotoxin. |
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| ISSN: | 0278-0240 1875-8630 |