Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report
Herpes simplex virus (HSV) hepatitis is an uncommon cause of fulminant hepatic failure, seen mostly in immunocompromised patients. Conventional treatment modalities for inflammatory bowel disease (IBD), such as steroids and azathioprine, have been known to cause HSV hepatitis. However, the reported...
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2019-07-01
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Online Access: | https://doi.org/10.1177/1179547619858979 |
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doaj-3e4e45cbb0fe40148416014dd8f8a50d2020-11-25T02:48:07ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762019-07-011210.1177/1179547619858979Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case ReportKanika GoelMark BunkerAnna BalogJan F SilvermanHerpes simplex virus (HSV) hepatitis is an uncommon cause of fulminant hepatic failure, seen mostly in immunocompromised patients. Conventional treatment modalities for inflammatory bowel disease (IBD), such as steroids and azathioprine, have been known to cause HSV hepatitis. However, the reported incidence of HSV hepatitis in IBD patients undergoing tumor necrosis factor (TNF)-α inhibitor therapy is very rare. In this case report, we describe a rare case of fulminant HSV hepatitis that developed in a patient with Crohn’s disease after treatment with the TNF-α inhibitor, adalimumab.https://doi.org/10.1177/1179547619858979 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kanika Goel Mark Bunker Anna Balog Jan F Silverman |
spellingShingle |
Kanika Goel Mark Bunker Anna Balog Jan F Silverman Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report Clinical Medicine Insights: Case Reports |
author_facet |
Kanika Goel Mark Bunker Anna Balog Jan F Silverman |
author_sort |
Kanika Goel |
title |
Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report |
title_short |
Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report |
title_full |
Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report |
title_fullStr |
Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report |
title_full_unstemmed |
Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report |
title_sort |
fulminant herpes simplex hepatitis secondary to adalimumab in crohn’s disease: a case report |
publisher |
SAGE Publishing |
series |
Clinical Medicine Insights: Case Reports |
issn |
1179-5476 |
publishDate |
2019-07-01 |
description |
Herpes simplex virus (HSV) hepatitis is an uncommon cause of fulminant hepatic failure, seen mostly in immunocompromised patients. Conventional treatment modalities for inflammatory bowel disease (IBD), such as steroids and azathioprine, have been known to cause HSV hepatitis. However, the reported incidence of HSV hepatitis in IBD patients undergoing tumor necrosis factor (TNF)-α inhibitor therapy is very rare. In this case report, we describe a rare case of fulminant HSV hepatitis that developed in a patient with Crohn’s disease after treatment with the TNF-α inhibitor, adalimumab. |
url |
https://doi.org/10.1177/1179547619858979 |
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