Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study

Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confi...

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Main Author: Bishal Khaniya
Format: Article
Language:English
Published: HEAD Nepal 2021-06-01
Series:Nepalese Medical Journal
Subjects:
Online Access:https://www.nepjol.info/index.php/nmj/article/view/37717
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spelling doaj-3e5480f7e8724c6cb9a3ce5cf80c9c1a2021-07-27T04:26:31ZengHEAD NepalNepalese Medical Journal2631-20932645-85862021-06-014144244510.3126/nmj.v4i1.3771734504Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years StudyBishal Khaniya0https://orcid.org/0000-0002-7191-0955Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, NepalIntroduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018. Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years. Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality.https://www.nepjol.info/index.php/nmj/article/view/37717endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma
collection DOAJ
language English
format Article
sources DOAJ
author Bishal Khaniya
spellingShingle Bishal Khaniya
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
Nepalese Medical Journal
endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma
author_facet Bishal Khaniya
author_sort Bishal Khaniya
title Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
title_short Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
title_full Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
title_fullStr Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
title_full_unstemmed Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
title_sort histopathological pattern of gynecological malignancies at tribhuvan university teaching hospital, nepal: a 3 years study
publisher HEAD Nepal
series Nepalese Medical Journal
issn 2631-2093
2645-8586
publishDate 2021-06-01
description Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018. Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years. Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality.
topic endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma
url https://www.nepjol.info/index.php/nmj/article/view/37717
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