Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confi...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
HEAD Nepal
2021-06-01
|
Series: | Nepalese Medical Journal |
Subjects: | |
Online Access: | https://www.nepjol.info/index.php/nmj/article/view/37717 |
id |
doaj-3e5480f7e8724c6cb9a3ce5cf80c9c1a |
---|---|
record_format |
Article |
spelling |
doaj-3e5480f7e8724c6cb9a3ce5cf80c9c1a2021-07-27T04:26:31ZengHEAD NepalNepalese Medical Journal2631-20932645-85862021-06-014144244510.3126/nmj.v4i1.3771734504Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years StudyBishal Khaniya0https://orcid.org/0000-0002-7191-0955Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, NepalIntroduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018. Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years. Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality.https://www.nepjol.info/index.php/nmj/article/view/37717endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bishal Khaniya |
spellingShingle |
Bishal Khaniya Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study Nepalese Medical Journal endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
author_facet |
Bishal Khaniya |
author_sort |
Bishal Khaniya |
title |
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_short |
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_full |
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_fullStr |
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_full_unstemmed |
Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_sort |
histopathological pattern of gynecological malignancies at tribhuvan university teaching hospital, nepal: a 3 years study |
publisher |
HEAD Nepal |
series |
Nepalese Medical Journal |
issn |
2631-2093 2645-8586 |
publishDate |
2021-06-01 |
description |
Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia.
Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018.
Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years.
Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality. |
topic |
endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
url |
https://www.nepjol.info/index.php/nmj/article/view/37717 |
work_keys_str_mv |
AT bishalkhaniya histopathologicalpatternofgynecologicalmalignanciesattribhuvanuniversityteachinghospitalnepala3yearsstudy |
_version_ |
1721280148794245120 |