ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES

Several methods have been used to relieve pain in neonates. The objective of this study was to assess the analgesic effect of 50% glucose and water during hepatitis B vaccination. In this randomized controlled trial, 90 term neonates were studied. Infants were randomly assigned to one of the three...

Full description

Bibliographic Details
Main Authors: M. Golestan, S. Akhavan Karbasi, M. Modares-Mosadegh M. Sadr-Bafghi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2007-12-01
Series:Acta Medica Iranica
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/3317
id doaj-3e59b182968d4977b287632afde66353
record_format Article
spelling doaj-3e59b182968d4977b287632afde663532020-11-25T01:29:00ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942007-12-01456ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES M. Golestan0 S. Akhavan Karbasi1 M. Modares-Mosadegh M. Sadr-Bafghi2 Several methods have been used to relieve pain in neonates. The objective of this study was to assess the analgesic effect of 50% glucose and water during hepatitis B vaccination. In this randomized controlled trial, 90 term neonates were studied. Infants were randomly assigned to one of the three equal sized groups. First, heart rates were measured by EKG monitor. Then, 2mL of either 50% glucose or sterile water was administered into the mouths of infants in groups one and two, respectively. No intervention was done for group three. During vaccination until three minutes after, crying of babies was taped. Heart rates were measured during injection until 60 seconds. Mean values of duration of crying for glucose, water, and no intervention groups were 21.1 s, 33.3 s, and 56.9 s, respectively, which were significantly different (P= 0.0003). Post hoc test revealed substantial differences between groups one and three (P= 0.0001) and between groups two and three (P= 0.006). However, groups one and two were not statistically different (P= 0.19). Moreover, heart rate did not rise significantly in any of those groups. Both 50% glucose and water showed analgesic effects in neonates. https://acta.tums.ac.ir/index.php/acta/article/view/3317
collection DOAJ
language English
format Article
sources DOAJ
author M. Golestan
S. Akhavan Karbasi
M. Modares-Mosadegh M. Sadr-Bafghi
spellingShingle M. Golestan
S. Akhavan Karbasi
M. Modares-Mosadegh M. Sadr-Bafghi
ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
Acta Medica Iranica
author_facet M. Golestan
S. Akhavan Karbasi
M. Modares-Mosadegh M. Sadr-Bafghi
author_sort M. Golestan
title ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
title_short ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
title_full ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
title_fullStr ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
title_full_unstemmed ANALGESIC EFFECTS OF GLUCOSE AND WATER IN NEONATES
title_sort analgesic effects of glucose and water in neonates
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 2007-12-01
description Several methods have been used to relieve pain in neonates. The objective of this study was to assess the analgesic effect of 50% glucose and water during hepatitis B vaccination. In this randomized controlled trial, 90 term neonates were studied. Infants were randomly assigned to one of the three equal sized groups. First, heart rates were measured by EKG monitor. Then, 2mL of either 50% glucose or sterile water was administered into the mouths of infants in groups one and two, respectively. No intervention was done for group three. During vaccination until three minutes after, crying of babies was taped. Heart rates were measured during injection until 60 seconds. Mean values of duration of crying for glucose, water, and no intervention groups were 21.1 s, 33.3 s, and 56.9 s, respectively, which were significantly different (P= 0.0003). Post hoc test revealed substantial differences between groups one and three (P= 0.0001) and between groups two and three (P= 0.006). However, groups one and two were not statistically different (P= 0.19). Moreover, heart rate did not rise significantly in any of those groups. Both 50% glucose and water showed analgesic effects in neonates.
url https://acta.tums.ac.ir/index.php/acta/article/view/3317
work_keys_str_mv AT mgolestan analgesiceffectsofglucoseandwaterinneonates
AT sakhavankarbasi analgesiceffectsofglucoseandwaterinneonates
AT mmodaresmosadeghmsadrbafghi analgesiceffectsofglucoseandwaterinneonates
_version_ 1725099134009999360