The Three-Dimensional Ultrastructure of the Human Alveolar Epithelium Revealed by Focused Ion Beam Electron Microscopy

The Three-Dimensional Ultrastructure of the Human Alveolar Epithelium Revealed by Focused Ion Beam Electron Microscopy

Thin type 1 alveolar epithelial (AE1) and surfactant producing type 2 alveolar epithelial (AE2) cells line the alveoli in the lung and are essential for normal lung function. Function is intimately interrelated to structure, so that detailed knowledge of the epithelial ultrastructure can significant...

Full description

Bibliographic Details
Main Authors:	Jan Philipp Schneider, Christoph Wrede, Christian Mühlfeld
Format:	Article
Language:	English
Published:	MDPI AG 2020-02-01
Series:	International Journal of Molecular Sciences
Subjects:	lung alveolus type 1 alveolar epithelial cell type 2 alveolar epithelial cell focused ion beam scanning electron microscopy 3d reconstruction
Online Access:	https://www.mdpi.com/1422-0067/21/3/1089

Similar Items

Characterization of air-liquid interface culture of A549 alveolar epithelial cells
by: J. Wu, et al.
Published: (2017-12-01)

Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids
by: Danying Liao, et al.
Published: (2020-06-01)

Corrigendum: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids
by: Danying Liao, et al.
Published: (2021-05-01)

Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
by: Konstantinos Gkatzis, et al.
Published: (2021-09-01)

A mammalian Wnt5a–Ror2–Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis
by: Kuan Zhang, et al.
Published: (2020-05-01)

Age-Related Structural and Functional Changes in the Mouse Lung
by: Henri Schulte, et al.
Published: (2019-12-01)

Lipidomic characterization and localization of phospholipids in the human lung[S]
by: Karin A. Zemski Berry, et al.
Published: (2017-05-01)

Improved Alveolar Dynamics and Structure After Alveolar Epithelial Type II Cell Transplantation in Bleomycin Induced Lung Fibrosis
by: Elena Lopez-Rodriguez, et al.
Published: (2021-02-01)

Linking Fibrotic Remodeling and Ultrastructural Alterations of Alveolar Epithelial Cells after Deletion of <i>Nedd4-2</i>
by: Theresa A. Engelmann, et al.
Published: (2021-07-01)

The Alveolar Epithelium Mechanisms of Injury and Repair
Published: (2020)

Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner
by: Deblina Chakraborty, et al.
Published: (2017-11-01)

Rcn3 Suppression Was Responsible for Partial Relief of Emphysema as Shown by Specific Type II Alveolar Epithelial Cell Rcn3 CKO Mouse Model
by: Zhang Q, et al.
Published: (2021-01-01)

Transcriptomic profiling of primary alveolar epithelial cell differentiation in human and rat
by: Crystal N. Marconett, et al.
Published: (2014-12-01)

Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis
by: Tanyalak Parimon, et al.
Published: (2020-03-01)

Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation
by: Chen Yao, et al.
Published: (2012-01-01)

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
by: Torsten Goldmann, et al.
Published: (2018-07-01)

Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells
by: Elhusseiny Mohamed Mahmud Abdelwahab, et al.
Published: (2019-09-01)

Effect of mycobacterial secretory proteins on the cellular integrity and cytokine profile of type II alveolar epithelial cells
by: Nidhi Adlakha, et al.
Published: (2012-01-01)

The role of miRNAs in alveolar epithelial cells in emphysema
by: Hassan Hayek, et al.
Published: (2021-11-01)

High density lipoprotein promoting proliferation and migration of type II alveolar epithelial cells during inflammation state
by: Zhongji Yu, et al.
Published: (2017-05-01)

Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549)
by: Esmaeil Mortaz, et al.
Published: (2017-04-01)

Nanoparticle Fate in Alveolar Epithelial Cells: Uptake, Distribution and Exocytosis
by: Edward Crandall, et al.
Published: (2020-01-01)

Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE<sub>2</sub>, PGD<sub>2</sub> and Their Receptors
by: Jihye Jung, et al.
Published: (2019-06-01)

In vitro effects of water-pipe smoke condensate on the endocytic activity of Type II alveolar epithelial cells (A549) with bacillus Calmette–Guérin
by: Ian M Adcock, et al.
Published: (2016-01-01)

Deletion of SMARCA4 impairs alveolar epithelial type II cells proliferation and aggravates pulmonary fibrosis in mice
by: Danyi Peng, et al.
Published: (2017-12-01)

The effects of BMMSC treatment on lung tissue degeneration in elderly macaques
by: Yu-kun Yang, et al.
Published: (2021-03-01)

Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin
by: Anita Sapoznikov, et al.
Published: (2015-11-01)

Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells
by: Tingting Fang, et al.
Published: (2021-06-01)

Alveolar type 2 epithelial cells in lung development and disease
by: Sitaraman, Sneha
Published: (2019)

Mycobacterium tuberculosis Primary Infection and Dissemination: A Critical Role for Alveolar Epithelial Cells
by: Michelle B. Ryndak, et al.
Published: (2019-08-01)

Alveolar-Capillary Membrane-Related Pulmonary Cells as a Target in Endotoxin-Induced Acute Lung Injury
by: Zuzana Nova, et al.
Published: (2019-02-01)

YY1 mediates TGF-β1-induced EMT and pro-fibrogenesis in alveolar epithelial cells
by: Chuyi Zhang, et al.
Published: (2019-11-01)

ER Stress is Involved in Epithelial-To-Mesenchymal Transition of Alveolar Epithelial Cells Exposed to a Hypoxic Microenvironment
by: Eva Delbrel, et al.
Published: (2019-03-01)

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling
by: Shanshan Song, et al.
Published: (2021-06-01)

Donor Site Evaluation: Anterior Iliac Crest Following Secondary Alveolar Bone Grafting
by: NANDAGOPAL VURA, et al.
Published: (2013-11-01)

Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model
by: Gan L, et al.
Published: (2016-11-01)

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus
by: Kosmider Beata, et al.
Published: (2012-06-01)

Endoplasmic Reticulum Stress Induces HRD1 to Protect Alveolar Type II Epithelial Cells from Apoptosis Induced by Cigarette Smoke Extract
by: Shuang-xiang Tan, et al.
Published: (2017-10-01)

Comparative efficacy of autologous alveolar bone grafting with autologous platelet-rich plasma and without platelet-rich plasma in cleft alveolus patients
by: Rohan Suhas Deshpande, et al.
Published: (2017-01-01)

Dexmedetomidine preconditioning protects against lipopolysaccharides-induced injury in the human alveolar epithelial cells
by: Lei Zhang, et al.