Relationship between Oxidative Stress, Circadian Rhythms, and AMD
This work reviews concepts regarding oxidative stress and the mechanisms by which endogenous and exogenous factors produce reactive oxygen species (ROS). It also surveys the relationships between oxidative stress, circadian rhythms, and retinal damage in humans, particularly those related to light a...
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2016-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2016/7420637 |
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doaj-3e83118640114d25a2280ae9373357882020-11-24T22:01:58ZengHindawi LimitedOxidative Medicine and Cellular Longevity1942-09001942-09942016-01-01201610.1155/2016/74206377420637Relationship between Oxidative Stress, Circadian Rhythms, and AMDMaría Luisa Fanjul-Moles0Germán Octavio López-Riquelme1Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510 Ciudad de México, DF, MexicoPosgrado en Ciencias Cognitivas, Universidad Autónoma del Estado de Morelos, Facultad de Humanidades, UAEM, Avenida Universidad No. 1001, Colonia Chamilpa, 62209 Cuernavaca, MOR, MexicoThis work reviews concepts regarding oxidative stress and the mechanisms by which endogenous and exogenous factors produce reactive oxygen species (ROS). It also surveys the relationships between oxidative stress, circadian rhythms, and retinal damage in humans, particularly those related to light and photodamage. In the first section, the production of ROS by different cell organelles and biomolecules and the antioxidant mechanisms that antagonize this damage are reviewed. The second section includes a brief review of circadian clocks and their relationship with the cellular redox state. In the third part of this work, the relationship between retinal damage and ROS is described. The last part of this work focuses on retinal degenerative pathology, age-related macular degeneration, and the relationships between this pathology, ROS, and light. Finally, the possible interactions between the retinal pigment epithelium (RPE), circadian rhythms, and this pathology are discussed.http://dx.doi.org/10.1155/2016/7420637 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
María Luisa Fanjul-Moles Germán Octavio López-Riquelme |
spellingShingle |
María Luisa Fanjul-Moles Germán Octavio López-Riquelme Relationship between Oxidative Stress, Circadian Rhythms, and AMD Oxidative Medicine and Cellular Longevity |
author_facet |
María Luisa Fanjul-Moles Germán Octavio López-Riquelme |
author_sort |
María Luisa Fanjul-Moles |
title |
Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
title_short |
Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
title_full |
Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
title_fullStr |
Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
title_full_unstemmed |
Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
title_sort |
relationship between oxidative stress, circadian rhythms, and amd |
publisher |
Hindawi Limited |
series |
Oxidative Medicine and Cellular Longevity |
issn |
1942-0900 1942-0994 |
publishDate |
2016-01-01 |
description |
This work reviews concepts regarding oxidative stress and the mechanisms by which endogenous and exogenous factors produce reactive oxygen species (ROS). It also surveys the relationships between oxidative stress, circadian rhythms, and retinal damage in humans, particularly those related to light and photodamage. In the first section, the production of ROS by different cell organelles and biomolecules and the antioxidant mechanisms that antagonize this damage are reviewed. The second section includes a brief review of circadian clocks and their relationship with the cellular redox state. In the third part of this work, the relationship between retinal damage and ROS is described. The last part of this work focuses on retinal degenerative pathology, age-related macular degeneration, and the relationships between this pathology, ROS, and light. Finally, the possible interactions between the retinal pigment epithelium (RPE), circadian rhythms, and this pathology are discussed. |
url |
http://dx.doi.org/10.1155/2016/7420637 |
work_keys_str_mv |
AT marialuisafanjulmoles relationshipbetweenoxidativestresscircadianrhythmsandamd AT germanoctaviolopezriquelme relationshipbetweenoxidativestresscircadianrhythmsandamd |
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