Atypical optic neuritis: An overview

• Main Authors: Prathama Sarkar, Amit Mehtani, H C Gandhi, Vinita Dubey, Parag Maroti Tembhurde, Mohit Kumar Gupta
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: atypical optic neuritis; infectious optic neuritis; myelin oligodendrocyte glycoprotein antibody; neuromyelitis optica; optic neuritis
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=1;spage=27;epage=35;aulast=Sarkar

Optic neuritis (ON) refers to conditions that involve inflammation of the optic nerve. Various autoantibodies have been found, which are associated with central nervous system inflammatory disorders and have provided much information about the immune targets and mechanisms that impact the prognosis, treatment, and recurrence of atypical ON. Therefore, neurologists and ophthalmologists together should work to find out clinical, laboratory, and imaging findings that may provide important clues to the etiology of atypical ON and its management. Various biomarkers have been identified to confirm and distinguish atypical optic neuritis from others. The purpose of this review is to present the current scenario of atypical ON and its clinical management.