Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response

Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response

Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac inj...

Full description

Bibliographic Details
Main Authors: Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10338-2
id doaj-3e96cf3e564a4e068419e2da632f2557
record_format Article
spelling doaj-3e96cf3e564a4e068419e2da632f25572021-05-11T11:37:00ZengNature Publishing GroupNature Communications2041-17232019-05-0110111410.1038/s41467-019-10338-2Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and responseSimon F. Merz0Sebastian Korste1Lea Bornemann2Lars Michel3Pia Stock4Anthony Squire5Camille Soun6Daniel R. Engel7Julia Detzer8Holger Lörchner9Dirk M. Hermann10Markus Kamler11Joachim Klode12Ulrike B. Hendgen-Cotta13Tienush Rassaf14Matthias Gunzer15Matthias Totzeck16Institute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDept. of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung ResearchDept. of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung ResearchDepartment of Neurology, University Hospital EssenDepartment of Thoracic and Cardiovascular Surgery, University Hospital EssenDepartment of Dermatology, Venerology and Allergology, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDetailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac injury responses using light sheet fluorescence microscopy.https://doi.org/10.1038/s41467-019-10338-2
collection DOAJ
language English
format Article
sources DOAJ
author Simon F. Merz
Sebastian Korste
Lea Bornemann
Lars Michel
Pia Stock
Anthony Squire
Camille Soun
Daniel R. Engel
Julia Detzer
Holger Lörchner
Dirk M. Hermann
Markus Kamler
Joachim Klode
Ulrike B. Hendgen-Cotta
Tienush Rassaf
Matthias Gunzer
Matthias Totzeck
spellingShingle Simon F. Merz
Sebastian Korste
Lea Bornemann
Lars Michel
Pia Stock
Anthony Squire
Camille Soun
Daniel R. Engel
Julia Detzer
Holger Lörchner
Dirk M. Hermann
Markus Kamler
Joachim Klode
Ulrike B. Hendgen-Cotta
Tienush Rassaf
Matthias Gunzer
Matthias Totzeck
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
Nature Communications
author_facet Simon F. Merz
Sebastian Korste
Lea Bornemann
Lars Michel
Pia Stock
Anthony Squire
Camille Soun
Daniel R. Engel
Julia Detzer
Holger Lörchner
Dirk M. Hermann
Markus Kamler
Joachim Klode
Ulrike B. Hendgen-Cotta
Tienush Rassaf
Matthias Gunzer
Matthias Totzeck
author_sort Simon F. Merz
title Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
title_short Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
title_full Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
title_fullStr Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
title_full_unstemmed Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
title_sort contemporaneous 3d characterization of acute and chronic myocardial i/r injury and response
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-05-01
description Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac injury responses using light sheet fluorescence microscopy.
url https://doi.org/10.1038/s41467-019-10338-2
work_keys_str_mv AT simonfmerz contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT sebastiankorste contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT leabornemann contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT larsmichel contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT piastock contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT anthonysquire contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT camillesoun contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT danielrengel contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT juliadetzer contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT holgerlorchner contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT dirkmhermann contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT markuskamler contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT joachimklode contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT ulrikebhendgencotta contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT tienushrassaf contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT matthiasgunzer contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
AT matthiastotzeck contemporaneous3dcharacterizationofacuteandchronicmyocardialirinjuryandresponse
_version_ 1721446284695437312

Similar Items