Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac inj...
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2019-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10338-2 |
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doaj-3e96cf3e564a4e068419e2da632f25572021-05-11T11:37:00ZengNature Publishing GroupNature Communications2041-17232019-05-0110111410.1038/s41467-019-10338-2Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and responseSimon F. Merz0Sebastian Korste1Lea Bornemann2Lars Michel3Pia Stock4Anthony Squire5Camille Soun6Daniel R. Engel7Julia Detzer8Holger Lörchner9Dirk M. Hermann10Markus Kamler11Joachim Klode12Ulrike B. Hendgen-Cotta13Tienush Rassaf14Matthias Gunzer15Matthias Totzeck16Institute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDept. of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung ResearchDept. of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung ResearchDepartment of Neurology, University Hospital EssenDepartment of Thoracic and Cardiovascular Surgery, University Hospital EssenDepartment of Dermatology, Venerology and Allergology, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-EssenDepartment of Cardiology and Vascular Medicine, University Hospital EssenDetailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac injury responses using light sheet fluorescence microscopy.https://doi.org/10.1038/s41467-019-10338-2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Simon F. Merz Sebastian Korste Lea Bornemann Lars Michel Pia Stock Anthony Squire Camille Soun Daniel R. Engel Julia Detzer Holger Lörchner Dirk M. Hermann Markus Kamler Joachim Klode Ulrike B. Hendgen-Cotta Tienush Rassaf Matthias Gunzer Matthias Totzeck |
spellingShingle |
Simon F. Merz Sebastian Korste Lea Bornemann Lars Michel Pia Stock Anthony Squire Camille Soun Daniel R. Engel Julia Detzer Holger Lörchner Dirk M. Hermann Markus Kamler Joachim Klode Ulrike B. Hendgen-Cotta Tienush Rassaf Matthias Gunzer Matthias Totzeck Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response Nature Communications |
author_facet |
Simon F. Merz Sebastian Korste Lea Bornemann Lars Michel Pia Stock Anthony Squire Camille Soun Daniel R. Engel Julia Detzer Holger Lörchner Dirk M. Hermann Markus Kamler Joachim Klode Ulrike B. Hendgen-Cotta Tienush Rassaf Matthias Gunzer Matthias Totzeck |
author_sort |
Simon F. Merz |
title |
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response |
title_short |
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response |
title_full |
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response |
title_fullStr |
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response |
title_full_unstemmed |
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response |
title_sort |
contemporaneous 3d characterization of acute and chronic myocardial i/r injury and response |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2019-05-01 |
description |
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensional investigation of acute and chronic cardiac injury responses using light sheet fluorescence microscopy. |
url |
https://doi.org/10.1038/s41467-019-10338-2 |
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