ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells

ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells

Abstract Background Alanine‐serine‐cysteine transporter 2 (ASCT2), a major glutamine transporter, is essential for cell growth and tumor development in a variety of cancers. However, the clinicopathological significance and pathological role of ASCT2 in OSCC (oral squamous cell carcinoma) lesions re...

Full description

Bibliographic Details
Main Authors: Yijun Luo, Wei Li, Zihang Ling, Qinchao Hu, Zhen Fan, Bin Cheng, Xiaoan Tao
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Cancer Medicine
Subjects:
ASCT2
glutamine
oral squamous cells carcinoma
ROS
Online Access:https://doi.org/10.1002/cam4.2965

Similar Items

Similar Items