Histomorfologia de órgãos-alvo de ratos diabéticos suplementados com noni (Morinda citrifolia)
Introduction: Type I Diabetes Mellitus (DM) is a multifactorial disease involving immune response, genetics and the environment. The use of medicinal plants for treatment and prevention of disease is very common; noni (Morinda citrifolia) is an example of one. Objective: To study the effect caused o...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Portuguese |
| Published: |
Universidade Nove de Julho
2011-01-01
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| Series: | ConScientiae Saúde |
| Online Access: | http://www.redalyc.org/articulo.oa?id=92921260008 |
| Summary: | Introduction: Type I Diabetes Mellitus (DM) is a multifactorial disease involving immune response, genetics and the environment. The use of medicinal plants for treatment and prevention of disease is very common; noni (Morinda citrifolia) is an example of one. Objective: To study the effect caused on the kidney, liver and spleen of rats with type I diabetes receiving a daily supplement of noni juice. Methods: A total of 21 rats were divided into three groups of seven animals each: group G0 - healthy animals not receiving the supplement; G1 - type I DM type animals receiving the supplement and G2 - type I DM type animals not receiving the supplement. Results: The spleen and liver showed no pathological changes in any group. Type I diabetic animals not receiving the supplement showed a slight thickening of the glomerular basement membrane. Conclusion: The use of noni juice for a period equal to thirty days does not cause pathological changes in the spleen and liver, but type I diabetic rats receiving the supplement appear to benefit from a nephroprotective effect. |
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| ISSN: | 1677-1028 1983-9324 |