COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series

Objective: Diabetes mellitus has been recognized as one of the comorbidities that predict the severity of illness in patients infected with COVID-19. The characteristics of patients presenting with diabetic ketoacidosis (DKA) and COVID-19 infection have not been described. Methods: We describe 5 pat...

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Main Authors: Ramya S. Gorthi, MD, Ghassan Kamel, MD, Sandeep Dhindsa, MD, Ravi P. Nayak, MD, FCCP
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:AACE Clinical Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520310117
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spelling doaj-3ec1c623722142bba3a5f03ea904a02b2021-05-01T04:35:57ZengElsevierAACE Clinical Case Reports2376-06052021-01-017169COVID-19 Presenting With Diabetic Ketoacidosis: A Case SeriesRamya S. Gorthi, MD0Ghassan Kamel, MD1Sandeep Dhindsa, MD2Ravi P. Nayak, MD, FCCP3Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MissouriDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MissouriDivision of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, Saint Louis, MissouriDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri; Address correspondence and reprint requests to Dr Ravi P. Nayak, Interim Chairman and Professor of Internal Medicine, Director, Division of Pulmonary, Critical Care, and Sleep Medicine, Director, Adult Cystic Fibrosis Program, Saint Louis University School of Medicine, 12 North FDT, 1402 S, Grand Avenue, Saint Louis, MO 63104-1004.Objective: Diabetes mellitus has been recognized as one of the comorbidities that predict the severity of illness in patients infected with COVID-19. The characteristics of patients presenting with diabetic ketoacidosis (DKA) and COVID-19 infection have not been described. Methods: We describe 5 patients with DKA and concomitant COVID-19 admitted to the intensive care unit of an academic medical center. Three patients had type 1 diabetes mellitus, and 2 patients had type 2 diabetes mellitus. Results: While DKA with an infectious etiology is a common presentation, we observed that the patients with DKA precipitated by COVID-19 presented with atypical symptoms. COVID-19 infection was revealed during search for an etiology of DKA. Conclusion: It is prudent to have a low threshold to screen for COVID-19 infection in patients with DKA.http://www.sciencedirect.com/science/article/pii/S2376060520310117diabetic ketoacidosisCOVID-19SARS-CoV2type 1 diabetes mellitustype 2 diabetes mellitus
collection DOAJ
language English
format Article
sources DOAJ
author Ramya S. Gorthi, MD
Ghassan Kamel, MD
Sandeep Dhindsa, MD
Ravi P. Nayak, MD, FCCP
spellingShingle Ramya S. Gorthi, MD
Ghassan Kamel, MD
Sandeep Dhindsa, MD
Ravi P. Nayak, MD, FCCP
COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
AACE Clinical Case Reports
diabetic ketoacidosis
COVID-19
SARS-CoV2
type 1 diabetes mellitus
type 2 diabetes mellitus
author_facet Ramya S. Gorthi, MD
Ghassan Kamel, MD
Sandeep Dhindsa, MD
Ravi P. Nayak, MD, FCCP
author_sort Ramya S. Gorthi, MD
title COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
title_short COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
title_full COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
title_fullStr COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
title_full_unstemmed COVID-19 Presenting With Diabetic Ketoacidosis: A Case Series
title_sort covid-19 presenting with diabetic ketoacidosis: a case series
publisher Elsevier
series AACE Clinical Case Reports
issn 2376-0605
publishDate 2021-01-01
description Objective: Diabetes mellitus has been recognized as one of the comorbidities that predict the severity of illness in patients infected with COVID-19. The characteristics of patients presenting with diabetic ketoacidosis (DKA) and COVID-19 infection have not been described. Methods: We describe 5 patients with DKA and concomitant COVID-19 admitted to the intensive care unit of an academic medical center. Three patients had type 1 diabetes mellitus, and 2 patients had type 2 diabetes mellitus. Results: While DKA with an infectious etiology is a common presentation, we observed that the patients with DKA precipitated by COVID-19 presented with atypical symptoms. COVID-19 infection was revealed during search for an etiology of DKA. Conclusion: It is prudent to have a low threshold to screen for COVID-19 infection in patients with DKA.
topic diabetic ketoacidosis
COVID-19
SARS-CoV2
type 1 diabetes mellitus
type 2 diabetes mellitus
url http://www.sciencedirect.com/science/article/pii/S2376060520310117
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