Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines

<p>Abstract</p> <p>Background</p> <p>Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic reactions suggests a potential way to discover drug targets.</p>...

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Bibliographic Details
Main Authors: Ching Wai-Ki, Zhou Xiaobo, Li Limin, Wang Ping
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/501