Resveratrol Induces the Expression of Interleukin-10 and Brain-Derived Neurotrophic Factor in BV2 Microglia under Hypoxia

Resveratrol Induces the Expression of Interleukin-10 and Brain-Derived Neurotrophic Factor in BV2 Microglia under Hypoxia

Microglia are the resident macrophages of the central nervous system (CNS) and play an important role in neuronal recovery by scavenging damaged neurons. However, overactivation of microglia leads to neuronal death that is associated with CNS disorders. Therefore, regulation of microglial activatio...

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Bibliographic Details
Main Authors: Juhyun Song, So Yeong Cheon, Wonsug Jung, Won Taek Lee, Jong Eun Lee
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
resveratrol
microglia
hypoxia
nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB)
interleukin-10 (IL-10)
brain-derived neurotrophic factor (BDNF)
Online Access:http://www.mdpi.com/1422-0067/15/9/15512

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http://www.mdpi.com/1422-0067/15/9/15512

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