MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY

MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY

Merkel cell carcinoma represents an aggressive histopathological subtype of skin cancer with a high propensity to spread via lymphatic route. Once the benefits of the sentinel lymph node detection have been proven in malignant melanoma, the effectiveness of the method was investigated further on in...

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Main Authors: Nicolae Bacalbasa, Irina Balescu, Mihai Dimitriu, Mihaela Vilcu, Iulian Brezean
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2019-03-01
Series:Romanian Medical Journal
Subjects:
merkel cell carcinoma
sentinel node biopsy
prognostic
Online Access:https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.1/RMJ_2019_1_Art-07.pdf
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spelling doaj-3ef428fd18bf4c07befa52be41bdbee52021-09-02T18:48:16ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2019-03-01661343710.37897/RMJ.2019.1.7MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSYNicolae Bacalbasa0Irina Balescu1Mihai Dimitriu2Mihaela Vilcu3Iulian Brezean4Center of Excellence in Translational Medicine, Fundeni Clinical Institute, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, RomaniaPonderas Academic Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Pantelimon Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, RomaniaMerkel cell carcinoma represents an aggressive histopathological subtype of skin cancer with a high propensity to spread via lymphatic route. Once the benefits of the sentinel lymph node detection have been proven in malignant melanoma, the effectiveness of the method was investigated further on in Merkel cell carcinoma, as long as the two tumoral subtypes seem to have a common embryological origin. Surprisingly, the results reported so far in Merkel cell carcinoma are rather confusing, the method not being so far associated as part of the standard therapeutic protocol. However, it seems that the method plays a certain role in identifying the high risk patients and further tailoring the therapeutic strategy. This is a literature review of the most eloquent studies conducted on this theme. https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.1/RMJ_2019_1_Art-07.pdfmerkel cell carcinomasentinel node biopsyprognostic
collection DOAJ
language English
format Article
sources DOAJ
author Nicolae Bacalbasa
Irina Balescu
Mihai Dimitriu
Mihaela Vilcu
Iulian Brezean
spellingShingle Nicolae Bacalbasa
Irina Balescu
Mihai Dimitriu
Mihaela Vilcu
Iulian Brezean
MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
Romanian Medical Journal
merkel cell carcinoma
sentinel node biopsy
prognostic
author_facet Nicolae Bacalbasa
Irina Balescu
Mihai Dimitriu
Mihaela Vilcu
Iulian Brezean
author_sort Nicolae Bacalbasa
title MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
title_short MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
title_full MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
title_fullStr MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
title_full_unstemmed MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY
title_sort merkel cell carcinoma – pro and cons aspects for sentinel lymph node biopsy
publisher Amaltea Medical Publishing House
series Romanian Medical Journal
issn 1220-5478
2069-606X
publishDate 2019-03-01
description Merkel cell carcinoma represents an aggressive histopathological subtype of skin cancer with a high propensity to spread via lymphatic route. Once the benefits of the sentinel lymph node detection have been proven in malignant melanoma, the effectiveness of the method was investigated further on in Merkel cell carcinoma, as long as the two tumoral subtypes seem to have a common embryological origin. Surprisingly, the results reported so far in Merkel cell carcinoma are rather confusing, the method not being so far associated as part of the standard therapeutic protocol. However, it seems that the method plays a certain role in identifying the high risk patients and further tailoring the therapeutic strategy. This is a literature review of the most eloquent studies conducted on this theme.
topic merkel cell carcinoma
sentinel node biopsy
prognostic
url https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.1/RMJ_2019_1_Art-07.pdf
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AT irinabalescu merkelcellcarcinomaproandconsaspectsforsentinellymphnodebiopsy
AT mihaidimitriu merkelcellcarcinomaproandconsaspectsforsentinellymphnodebiopsy
AT mihaelavilcu merkelcellcarcinomaproandconsaspectsforsentinellymphnodebiopsy
AT iulianbrezean merkelcellcarcinomaproandconsaspectsforsentinellymphnodebiopsy
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