Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a complex disease resulting in respiratory failure and represents the third leading cause of global death. The two classical phenotypes of COPD are chronic bronchitis and emphysema. Owing to similarities between chronic bronchitis and the auto...
Main Authors: | Jack H. Wellmerling, Sheng-Wei Chang, Eunsoo Kim, Wissam H. Osman, Prosper N. Boyaka, Michael T. Borchers, Estelle Cormet-Boyaka |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12931-019-1170-3 |
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