MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1.

MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1.

MicroRNAs are a class of small noncoding RNAs that function as critical gene regulators through targeting mRNAs for translational repression or degradation. In this study, we showed that miR-128 expression levels were decreased in glioma, and identified p70S6K1 as a novel direct target of miR-128. O...

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Main Authors: Zhu-mei Shi, Jing Wang, Zhiping Yan, Yong-ping You, Chong-yong Li, Xu Qian, Yu Yin, Peng Zhao, Ying-ying Wang, Xie-feng Wang, Ming-na Li, Ling-Zhi Liu, Ning Liu, Bing-Hua Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307714?pdf=render

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