Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responses

Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responses

<p>Abstract</p> <p>Background</p> <p>Lentiviruses such as human and simian immunodeficiency viruses (HIV and SIV) undergo continual evolution in the host. Previous studies showed that the late-stage variants of SIV that evolve in one host replicate to significantly high...

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Bibliographic Details
Main Authors: Forthal Donald N, Wu Xueling, Piantadosi Anne, Eastman Dawnnica, Landucci Gary, Kimata Jason T, Overbaugh Julie
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/90

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