Ammonium is toxic for aging yeast cells, inducing death and shortening of the chronological lifespan.
Here we show that in aging Saccharomyces cerevisiae (budding yeast) cells, NH(4) (+) induces cell death associated with shortening of chronological life span. This effect is positively correlated with the concentration of NH(4) (+) added to the culture medium and is particularly evident when cells a...
Main Authors: | Júlia Santos, Maria João Sousa, Cecília Leão |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3352862?pdf=render |
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