Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report

Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report

Papillary tumor of the pineal region (PTPR) is a rare brain tumor that probably arises from ependymal cells. There are no known systemic treatments for PTPR once it is refractory to surgery and radiation. We present the first case of a durable radiographic and clinical response of a PTPR to bevacizu...

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Bibliographic Details
Main Authors: Adam L. Cohen, Karen Salzman, Cheryl Palmer, Randy Jensen, Howard Colman
Format: Article
Language:English
Published: Karger Publishers 2013-08-01
Series:Case Reports in Oncology
Subjects:
Pineal tumor
Bevacizumab
Angiogenesis
Online Access:http://www.karger.com/Article/FullText/354753
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spelling doaj-3f422e8452874a2fa20a9e4a444d35562020-11-24T22:35:19ZengKarger PublishersCase Reports in Oncology1662-65752013-08-016243444010.1159/000354753354753Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First ReportAdam L. CohenKaren SalzmanCheryl PalmerRandy JensenHoward ColmanPapillary tumor of the pineal region (PTPR) is a rare brain tumor that probably arises from ependymal cells. There are no known systemic treatments for PTPR once it is refractory to surgery and radiation. We present the first case of a durable radiographic and clinical response of a PTPR to bevacizumab, an antibody against vascular endothelial growth factor, despite multiple prior treatments. Bevacizumab may be an effective treatment for PTPR.http://www.karger.com/Article/FullText/354753Pineal tumorBevacizumabAngiogenesis
collection DOAJ
language English
format Article
sources DOAJ
author Adam L. Cohen
Karen Salzman
Cheryl Palmer
Randy Jensen
Howard Colman
spellingShingle Adam L. Cohen
Karen Salzman
Cheryl Palmer
Randy Jensen
Howard Colman
Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
Case Reports in Oncology
Pineal tumor
Bevacizumab
Angiogenesis
author_facet Adam L. Cohen
Karen Salzman
Cheryl Palmer
Randy Jensen
Howard Colman
author_sort Adam L. Cohen
title Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
title_short Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
title_full Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
title_fullStr Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
title_full_unstemmed Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report
title_sort bevacizumab is effective for recurrent papillary tumor of the pineal region: first report
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2013-08-01
description Papillary tumor of the pineal region (PTPR) is a rare brain tumor that probably arises from ependymal cells. There are no known systemic treatments for PTPR once it is refractory to surgery and radiation. We present the first case of a durable radiographic and clinical response of a PTPR to bevacizumab, an antibody against vascular endothelial growth factor, despite multiple prior treatments. Bevacizumab may be an effective treatment for PTPR.
topic Pineal tumor
Bevacizumab
Angiogenesis
url http://www.karger.com/Article/FullText/354753
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AT karensalzman bevacizumabiseffectiveforrecurrentpapillarytumorofthepinealregionfirstreport
AT cherylpalmer bevacizumabiseffectiveforrecurrentpapillarytumorofthepinealregionfirstreport
AT randyjensen bevacizumabiseffectiveforrecurrentpapillarytumorofthepinealregionfirstreport
AT howardcolman bevacizumabiseffectiveforrecurrentpapillarytumorofthepinealregionfirstreport
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