Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria
Objective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT...
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doaj-3f51904f5b9147e792564937d82bd6cf2020-11-25T00:30:05ZengHindawi LimitedTuberculosis Research and Treatment2090-150X2090-15182010-01-01201010.1155/2010/241659241659Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, NigeriaLovett Lawson0Mohammed A. Yassin1Alex N. Onuoha2Andrew Ramsay3Rachel R. M. Anderson de Cuevas4Sally Theobald5Peter D. O. Davies6Luis E. Cuevas7Zankli Medical Centre, Plot 1021, B5 Shehu Yar'adua Way, P.O. Box 7745, Abuja, NigeriaLiverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UKZankli Medical Centre, Plot 1021, B5 Shehu Yar'adua Way, P.O. Box 7745, Abuja, NigeriaLiverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UKFaculty of Medicine, University of Liverpool, Liverpool L693Bx, UKLiverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UKObjective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT-960. All patients had lung X-rays and screened for HIV. Results. were more likely to be smear-positive than females (262/774 [34%] and 137/547 [25%], P<.01), but similar proportions of males and females were culture-positive (437/691 [63%] and 294/495 [59%], P=.09). 317/626 (50.6%) males and 249/419 (59.4%) females were HIV-positive (P<.005). Among culture-positives patients, HIV-infected males were less likely to have positive smears than HIV-negative males (49.2% versus 66%, P=.001). Among females, smear positivity did not vary with HIV (46.4% for HIV-positive and 52.9% for HIV-negative, P=.38). Of 274 culture-confirmed TB cases, 226 (82.5%) had cavities, and 271 (99%) had ≥1 lung areas affected. HIV-positive males were more likely to have lung cavities than HIV-positive females (85% versus 69%, P<.04) and to have ≥3 lung areas affected (P=.03). Conclusion. Differences in the yield of smear-microscopy, culture and X-rays on presentation are due to several factors including HIV coinfection and gender.http://dx.doi.org/10.1155/2010/241659 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lovett Lawson Mohammed A. Yassin Alex N. Onuoha Andrew Ramsay Rachel R. M. Anderson de Cuevas Sally Theobald Peter D. O. Davies Luis E. Cuevas |
spellingShingle |
Lovett Lawson Mohammed A. Yassin Alex N. Onuoha Andrew Ramsay Rachel R. M. Anderson de Cuevas Sally Theobald Peter D. O. Davies Luis E. Cuevas Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria Tuberculosis Research and Treatment |
author_facet |
Lovett Lawson Mohammed A. Yassin Alex N. Onuoha Andrew Ramsay Rachel R. M. Anderson de Cuevas Sally Theobald Peter D. O. Davies Luis E. Cuevas |
author_sort |
Lovett Lawson |
title |
Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria |
title_short |
Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria |
title_full |
Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria |
title_fullStr |
Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria |
title_full_unstemmed |
Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria |
title_sort |
yield of smear microscopy and radiological findings of male and female patients with tuberculosis in abuja, nigeria |
publisher |
Hindawi Limited |
series |
Tuberculosis Research and Treatment |
issn |
2090-150X 2090-1518 |
publishDate |
2010-01-01 |
description |
Objective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT-960. All patients had lung X-rays and screened for HIV. Results. were more likely to be smear-positive than females (262/774 [34%] and 137/547 [25%], P<.01), but similar proportions of males and females were culture-positive (437/691 [63%] and 294/495 [59%], P=.09). 317/626 (50.6%) males and 249/419 (59.4%) females were HIV-positive (P<.005). Among culture-positives patients, HIV-infected males were less likely to have positive smears than HIV-negative males (49.2% versus 66%, P=.001). Among females, smear positivity did not vary with HIV (46.4% for HIV-positive and 52.9% for HIV-negative, P=.38). Of 274 culture-confirmed TB cases, 226 (82.5%) had cavities, and 271 (99%) had ≥1 lung areas affected. HIV-positive males were more likely to have lung cavities than HIV-positive females (85% versus 69%, P<.04) and to have ≥3 lung areas affected (P=.03).
Conclusion. Differences in the yield of smear-microscopy, culture and X-rays on presentation are due to several factors including HIV coinfection and gender. |
url |
http://dx.doi.org/10.1155/2010/241659 |
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