RIG-I and dsRNA-induced IFNbeta activation.

RIG-I and dsRNA-induced IFNbeta activation.

Except for viruses that initiate RNA synthesis with a protein primer (e.g., picornaviruses), most RNA viruses initiate RNA synthesis with an NTP, and at least some of their viral (ppp)RNAs remain unblocked during the infection. Consistent with this, most viruses require RIG-I to mount an innate immu...

Full description

Bibliographic Details
Main Authors: Stéphane Hausmann, Jean-Baptiste Marq, Caroline Tapparel, Daniel Kolakofsky, Dominique Garcin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2607022?pdf=render

Internet

http://europepmc.org/articles/PMC2607022?pdf=render

Similar Items