PARP1-Driven Apoptosis in Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is considered a malignancy resulting from defects in apoptosis. For this reason, targeting apoptotic pathways in CLL may be valuable for its management. Poly [ADP-ribose] polymerase 1 (PARP1) is the main member of a family of nuclear enzymes that act as DNA damage...
Main Authors: | Panagiotis T. Diamantopoulos, Maria Sofotasiou, Vasiliki Papadopoulou, Katerina Polonyfi, Theodoros Iliakis, Nora-Athina Viniou |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2014/106713 |
Similar Items
-
Clinical considerations about the coexistence of melanoma and chronic lymphocytic leukemia in the era of targeted therapies, triggered by rare clinical scenarios. A case series and review of the literature
by: Panagiotis T. Diamantopoulos, et al.
Published: (2020-10-01) -
An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia
by: Theodoros Iliakis, et al.
Published: (2014-01-01) -
Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
by: Gero Knittel, et al.
Published: (2017-07-01) -
Reappraising prognosis in chronic lymphocytic leukemia
by: Baliakas, Panagiotis
Published: (2016) -
In Vitro Drug Sensitivity and Apoptosis in Chronic Lymphocytic Leukemia
by: Norberg, Maria
Published: (2010)