Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review
A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, an...
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Korean Pediatric Society
2019-11-01
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Online Access: | http://kjp.or.kr/upload/pdf/kjp-2019-00668.pdf |
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doaj-3f9c32e66f804537a3c13af3f14f20a52020-11-25T01:39:57ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582019-11-01621140540910.3345/kjp.2019.0066820125553576Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic reviewEnsiyeh Jenabi0Sara Ataei1Saeid Bashirian2 Pediatric Developmental Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran Social Determinants of Health Research Center, Hamadan University of Medical Sciences, Hamadan, IranA structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the Delphi checklist. Due to the heterogeneity of the findings, a meta-analysis was not possible. Drug interventions for the treatment of sleep disorders in patients with ASD included melatonin, atomoxetine, and risperidone. Atomoxetine had no effect on sleep disorders in patients with ASD. A total of 10 studies were reviewed. Melatonin appears to be useful for the treatment of sleep problems in patients with ASD, but further studies are needed to determine the effects of other drugs.http://kjp.or.kr/upload/pdf/kjp-2019-00668.pdfdrugsleep disordersautism spectrum disordersmeta-analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ensiyeh Jenabi Sara Ataei Saeid Bashirian |
spellingShingle |
Ensiyeh Jenabi Sara Ataei Saeid Bashirian Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review Korean Journal of Pediatrics drug sleep disorders autism spectrum disorders meta-analysis |
author_facet |
Ensiyeh Jenabi Sara Ataei Saeid Bashirian |
author_sort |
Ensiyeh Jenabi |
title |
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
title_short |
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
title_full |
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
title_fullStr |
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
title_full_unstemmed |
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
title_sort |
evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review |
publisher |
Korean Pediatric Society |
series |
Korean Journal of Pediatrics |
issn |
1738-1061 2092-7258 |
publishDate |
2019-11-01 |
description |
A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the Delphi checklist. Due to the heterogeneity of the findings, a meta-analysis was not possible. Drug interventions for the treatment of sleep disorders in patients with ASD included melatonin, atomoxetine, and risperidone. Atomoxetine had no effect on sleep disorders in patients with ASD. A total of 10 studies were reviewed. Melatonin appears to be useful for the treatment of sleep problems in patients with ASD, but further studies are needed to determine the effects of other drugs. |
topic |
drug sleep disorders autism spectrum disorders meta-analysis |
url |
http://kjp.or.kr/upload/pdf/kjp-2019-00668.pdf |
work_keys_str_mv |
AT ensiyehjenabi evaluationofdruginterventionsforthetreatmentofsleepdisordersinchildrenwithautismspectrumdisordersasystematicreview AT saraataei evaluationofdruginterventionsforthetreatmentofsleepdisordersinchildrenwithautismspectrumdisordersasystematicreview AT saeidbashirian evaluationofdruginterventionsforthetreatmentofsleepdisordersinchildrenwithautismspectrumdisordersasystematicreview |
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1725048213254176768 |