Tiossemicarbazonas: métodos de obtenção, aplicações sintéticas e importância biológica Thiosemicarbazones: preparation methods, synthetic applications and biological importance

<abstract language="eng">Thiosemicarbazones are a class of compounds known by their chemical and biological properties, such as antitumor, antibacterial, antiviral and antiprotozoal activity. Their ability to form chelates with metals has great importance in their biological activiti...

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Bibliographic Details
Main Authors: Rômulo P. Tenório, Alexandre J. S. Góes, José G. de Lima, Antônio R. de Faria, Antônio J. Alves, Thiago M. de Aquino
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2005-12-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422005000600018
Description
Summary:<abstract language="eng">Thiosemicarbazones are a class of compounds known by their chemical and biological properties, such as antitumor, antibacterial, antiviral and antiprotozoal activity. Their ability to form chelates with metals has great importance in their biological activities. Their synthesis is very simple, versatile and clean, usually giving high yields. They are largely employed as intermediates, in the synthesis of others compounds. This article is a survey of some of these characteristics showing their great importance to organic and medicinal chemistry.
ISSN:0100-4042
1678-7064