The Role of 18F-FDG PET/CT in the Diagnosis of Malignant Pleural Mesothelioma
Objective: We aimed to investigate the diagnostic efficiency of pleural thickness and mediastinal lymph nodes, size and SUVmax values in patients with a pre-diagnosis of malignant pleural mesothelioma (MPM) who underwent 18F-FDG PET/CT imaging. Methods: Fifty-four patients who were admitted to ou...
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| Format: | Article |
| Language: | English |
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Dicle University Medical School
2021-06-01
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| Series: | Dicle Medical Journal |
| Subjects: | |
| Online Access: | http://diclemedj.org/upload/sayi/81/Dicle%20Med%20J-04650.pdf |
| Summary: | Objective: We aimed to investigate the diagnostic efficiency of pleural thickness and mediastinal lymph nodes, size and
SUVmax values in patients with a pre-diagnosis of malignant pleural mesothelioma (MPM) who underwent 18F-FDG
PET/CT imaging.
Methods: Fifty-four patients who were admitted to our clinic with a diagnosis of MPM and had 18F-FDG PET/CT imaging
between May 2018 and February 2020 were retrospectively analyzed. 28 of the patients were female (%51,8) and 26
were male (%48,2) and their average age was 58,8. Pleural thickness values of all patients, sizes of mediastinal lymph
nodes and SUVmax values of all lesions were measured. Histopathological examination after PET/CT imaging revealed
MPM in 23 patients, benign pleural disease (BPH) in 20, and metastatic pleural disease (MPH) in 11 patients.
Results: In the comparison between all groups in terms of median SUVmax value of pleural thickness; statistical
significance was found (p=0.003). Median SUVmax parameter of pleural thickness in paired group comparisons; The
median SUVmax value of the BPH group was found to be statistically significantly lower than MPM and MPH (p values
p:0.034 and p:0.023 respectively). In other parameters, when MPM and other groups were compared, no statistically
significant difference was found. When the cut-off value of SUVmax for detecting MPM group was taken as 6,75, it had
%69,6 sensitivity and %67,6 specificity, and a statistically significant difference was found.
Conclusion: It was concluded that the median SUVmax value of pleural thickness can be used to distinguish malignant
pleural mesothelioma from other pleural pathologies. |
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| ISSN: | 1300-2945 1308-9889 |