The First Report of Immune Reconstitution Inflammatory Syndrome Complicated by Jarisch-Herxheimer Reaction

Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who present...

Full description

Bibliographic Details
Main Authors: Michelle DallaPiazza MD, Matthew Jiro Akiyama MD, MSc
Format: Article
Language:English
Published: SAGE Publishing 2017-07-01
Series:Journal of the International Association of Providers of AIDS Care
Online Access:https://doi.org/10.1177/2325957417702484
Description
Summary:Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who presented with mass lesions involving the skin, subcutaneous tissues, muscle, and bone. The diagnosis of Bartonella quintana BA was confirmed by serum polymerase chain reaction. The patient’s treatment course was complicated by both IRIS and Jarisch-Herxheimer reaction. The case had a favorable outcome with supportive care and continuation of ART and doxycycline.
ISSN:2325-9574
2325-9582