Clinical significance and biological role of cancer‐derived Type I collagen in lung and esophageal cancers

Background Extracellular matrix (ECM) is remodeled during carcinogenesis. An abundant constituent of ECM is collagen. Type I collagen is secreted by fibroblasts, is important for tumor growth and epithelial‐mesenchymal transition, and may also be secreted by cancer cells. However, the role and funct...

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Bibliographic Details
Main Authors: Shuo Fang, Yongdong Dai, Yan Mei, Mingming Yang, Liang Hu, Hong Yang, Xininyuan Guan, Jiangchao Li
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.12947

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