HapSolo: an optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding
Abstract Background Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not pro...
Main Authors: | Edwin A. Solares, Yuan Tao, Anthony D. Long, Brandon S. Gaut |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-020-03939-y |
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