Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications
Nanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogel...
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doaj-3ff77a3d83654a60b43588c67099571c2020-11-25T02:36:54ZengMDPI AGGels2310-28612020-07-016202010.3390/gels6030020Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical ApplicationsSobhan Ghaeini-Hesaroeiye0Hossein Razmi Bagtash1Soheil Boddohi2Ebrahim Vasheghani-Farahani3Esmaiel Jabbari4Biomedical Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran 14115, IranBiomedical Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran 14115, IranBiomedical Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran 14115, IranBiomedical Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran 14115, IranBiomimetic Materials and Tissue Engineering Laboratory, Department of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USANanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogels is their tunable responsiveness to external stimuli. In this review, thermosensitive nanogels are discussed, with a focus on moieties in their chemical structure which are responsible for thermosensitivity. These thermosensitive moieties can be classified into four groups, namely, polymers bearing amide groups, ether groups, vinyl ether groups and hydrophilic polymers bearing hydrophobic groups. These novel thermoresponsive nanogels provide effective drug delivery systems and tissue regeneration constructs for treating patients in many clinical applications, such as targeted, sustained and controlled release.https://www.mdpi.com/2310-2861/6/3/20nanogelsthermoresponsivedrug delivery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sobhan Ghaeini-Hesaroeiye Hossein Razmi Bagtash Soheil Boddohi Ebrahim Vasheghani-Farahani Esmaiel Jabbari |
spellingShingle |
Sobhan Ghaeini-Hesaroeiye Hossein Razmi Bagtash Soheil Boddohi Ebrahim Vasheghani-Farahani Esmaiel Jabbari Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications Gels nanogels thermoresponsive drug delivery |
author_facet |
Sobhan Ghaeini-Hesaroeiye Hossein Razmi Bagtash Soheil Boddohi Ebrahim Vasheghani-Farahani Esmaiel Jabbari |
author_sort |
Sobhan Ghaeini-Hesaroeiye |
title |
Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications |
title_short |
Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications |
title_full |
Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications |
title_fullStr |
Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications |
title_full_unstemmed |
Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications |
title_sort |
thermoresponsive nanogels based on different polymeric moieties for biomedical applications |
publisher |
MDPI AG |
series |
Gels |
issn |
2310-2861 |
publishDate |
2020-07-01 |
description |
Nanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogels is their tunable responsiveness to external stimuli. In this review, thermosensitive nanogels are discussed, with a focus on moieties in their chemical structure which are responsible for thermosensitivity. These thermosensitive moieties can be classified into four groups, namely, polymers bearing amide groups, ether groups, vinyl ether groups and hydrophilic polymers bearing hydrophobic groups. These novel thermoresponsive nanogels provide effective drug delivery systems and tissue regeneration constructs for treating patients in many clinical applications, such as targeted, sustained and controlled release. |
topic |
nanogels thermoresponsive drug delivery |
url |
https://www.mdpi.com/2310-2861/6/3/20 |
work_keys_str_mv |
AT sobhanghaeinihesaroeiye thermoresponsivenanogelsbasedondifferentpolymericmoietiesforbiomedicalapplications AT hosseinrazmibagtash thermoresponsivenanogelsbasedondifferentpolymericmoietiesforbiomedicalapplications AT soheilboddohi thermoresponsivenanogelsbasedondifferentpolymericmoietiesforbiomedicalapplications AT ebrahimvasheghanifarahani thermoresponsivenanogelsbasedondifferentpolymericmoietiesforbiomedicalapplications AT esmaieljabbari thermoresponsivenanogelsbasedondifferentpolymericmoietiesforbiomedicalapplications |
_version_ |
1724798072188305408 |