Eosinophilic fasciitis
Eosinophilic fasciitis is a rare connective tissue disease with unclear etiology and pathogenesis. It is classified as a scleroderma-like syndrome. The disease is characterized by fibrosis of the skin and subcutaneous tissues with significant thickening of fascia. Visceral involvement is rare. Chara...
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doaj-3ff98b457924457a96e97ad9c9c461f72020-11-24T22:39:54ZengIndex Copernicus International S.A.Postępy Higieny i Medycyny Doświadczalnej0032-54491732-26932015-01-016948849510.5604/01.3001.0009.652301.3001.0009.6523Eosinophilic fasciitisKarolina Niklas0Arkadiusz Niklas1Mariusz Puszczewicz2Katedra i Klinika Reumatologii i Chorób Wewnętrznych Uniwersytetu Medycznego w PoznaniuKlinika Hipertensjologii, Angiologii i Chorób Wewnętrznych Uniwersytetu Medycznego w PoznaniuKatedra i Klinika Reumatologii i Chorób Wewnętrznych Uniwersytetu Medycznego w PoznaniuEosinophilic fasciitis is a rare connective tissue disease with unclear etiology and pathogenesis. It is classified as a scleroderma-like syndrome. The disease is characterized by fibrosis of the skin and subcutaneous tissues with significant thickening of fascia. Visceral involvement is rare. Characteristic feature in laboratory tests is peripheral blood eosinophilia. Differential diagnosis should be performed, including ruling out systemic sclerosis, nephrogenic systemic fibrosis, eosinophilia-myalgia syndrome, scleromyxedema, hypereosinophilic syndrome or Churg-Strauss syndrome. Final diagnosis is confirmed by histopathological examination. In treatment of the disease corticosteroids and/or immunosuppressive drugs are used. Some other drugs showed activity in this disease e.g. dapsone, infiximab or rituximab. Prognosis is rather good but sometimes a long-term treatment is necessary. In this paper we summarized the current knowledge on eosinophilic fasciitis. http://phmd.pl/gicid/01.3001.0009.6523eosinophilic fasciitisShulman diseaseimmunosuppressive treatmenteozynofilowe zapalenie powięzizespół Shulmanaleczenie immunosupresyjne |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Karolina Niklas Arkadiusz Niklas Mariusz Puszczewicz |
spellingShingle |
Karolina Niklas Arkadiusz Niklas Mariusz Puszczewicz Eosinophilic fasciitis Postępy Higieny i Medycyny Doświadczalnej eosinophilic fasciitis Shulman disease immunosuppressive treatment eozynofilowe zapalenie powięzi zespół Shulmana leczenie immunosupresyjne |
author_facet |
Karolina Niklas Arkadiusz Niklas Mariusz Puszczewicz |
author_sort |
Karolina Niklas |
title |
Eosinophilic fasciitis |
title_short |
Eosinophilic fasciitis |
title_full |
Eosinophilic fasciitis |
title_fullStr |
Eosinophilic fasciitis |
title_full_unstemmed |
Eosinophilic fasciitis |
title_sort |
eosinophilic fasciitis |
publisher |
Index Copernicus International S.A. |
series |
Postępy Higieny i Medycyny Doświadczalnej |
issn |
0032-5449 1732-2693 |
publishDate |
2015-01-01 |
description |
Eosinophilic fasciitis is a rare connective tissue disease with unclear etiology and pathogenesis. It is classified as a scleroderma-like syndrome. The disease is characterized by fibrosis of the skin and subcutaneous tissues with significant thickening of fascia. Visceral involvement is rare. Characteristic feature in laboratory tests is peripheral blood eosinophilia. Differential diagnosis should be performed, including ruling out systemic sclerosis, nephrogenic systemic fibrosis, eosinophilia-myalgia syndrome, scleromyxedema, hypereosinophilic syndrome or Churg-Strauss syndrome. Final diagnosis is confirmed by histopathological examination. In treatment of the disease corticosteroids and/or immunosuppressive drugs are used. Some other drugs showed activity in this disease e.g. dapsone, infiximab or rituximab. Prognosis is rather good but sometimes a long-term treatment is necessary. In this paper we summarized the current knowledge on eosinophilic fasciitis.
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topic |
eosinophilic fasciitis Shulman disease immunosuppressive treatment eozynofilowe zapalenie powięzi zespół Shulmana leczenie immunosupresyjne |
url |
http://phmd.pl/gicid/01.3001.0009.6523 |
work_keys_str_mv |
AT karolinaniklas eosinophilicfasciitis AT arkadiuszniklas eosinophilicfasciitis AT mariuszpuszczewicz eosinophilicfasciitis |
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1725706938060111872 |