Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report
Introduction Necrolytic migratory erythema (NME) is a disorder that is recognized by reddish, migrating areas of blistering that heal with pigmentation. It is a characteristic rash that is often recognized by its distinct appearance and history. It has strong association with glucagonoma, a pancrea...
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Format: | Article |
Language: | English |
Published: |
Bulgarian Association of Young Surgeons
2020-10-01
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Series: | International Journal of Surgery and Medicine |
Subjects: | |
Online Access: | http://www.ejos.org/index.php?fulltxt=302645291&fulltxtj=136&fulltxtp=136-1591463468.pdf |
Summary: | Introduction
Necrolytic migratory erythema (NME) is a disorder that is recognized by reddish, migrating areas of blistering that heal with pigmentation. It is a characteristic rash that is often recognized by its distinct appearance and history. It has strong association with glucagonoma, a pancreatic neuroendocrine tumor arising from the alpha type islet cells. In such cases NME presents as a paraneoplastic manifestation of the disease. The diagnosis of this rare tumor depends on high index of suspicion on the basis of history and examination and relevant pathological and radiological investigations. This tumor is potentially curable by surgery.
Case Presentation
In this article the authors describe a 36 years old female patient with NME and a multifocal pancreatic neuroendocrine tumor with clinical features of glucagonoma syndrome. After investigations she underwent total pancreatectomy and within a few days her skin lesions and clinical symptoms started improving.
Conclusion
Prompt diagnosis and management are of paramount importance in the management of glucagonoma. It is possible if there is high index of suspicion and the management is done appropriately. |
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ISSN: | 2367-699X 2367-699X |