Global analysis of A-to-I RNA editing reveals association with common disease variants
RNA editing modifies transcripts and may alter their regulation or function. In humans, the most common modification is adenosine to inosine (A-to-I). We examined the global characteristics of RNA editing in 4,301 human tissue samples. More than 1.6 million A-to-I edits were identified in 62% of all...
Main Authors: | Oscar Franzén, Raili Ermel, Katyayani Sukhavasi, Rajeev Jain, Anamika Jain, Christer Betsholtz, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Josefin Skogsberg, Ke Hao, Eric E. Schadt, Johan L.M. Björkegren |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4466.pdf |
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