A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine
The title compound, C17H15N3O2, is a monoclinic polymorph (P21/c with Z′ = 1) of the previously reported triclinic (P-1 with Z′ = 2) form [Gajera et al. (2013). Acta Cryst. E69, o736–o737]. The molecule in the monoclinic polymorph features a central pyrazolyl ring with an N-bound p-tolyl group and a...
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doaj-403f7757b9564d268459e52209f0c7ab2020-11-25T00:12:31ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902015-10-0171101121112410.1107/S2056989015016023hb7490A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amineMukesh M. Jotani0Nilesh N. Gajera1Mukesh C. Patel2Herman H. Y. Sung3Edward R. T. Tiekink4Department of Physics, Bhavan's Sheth R. A. College of Science, Ahmedabad, Gujarat 380 001, IndiaP. S. Science and H. D. Patel Arts College, S. V. Campus, Kadi, Gujarat 382 715, IndiaP. S. Science and H. D. Patel Arts College, S. V. Campus, Kadi, Gujarat 382 715, IndiaDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People's Republic of ChinaDepartment of Chemistry, University of Malaya, 50603 Kuala Lumpur, MalaysiaThe title compound, C17H15N3O2, is a monoclinic polymorph (P21/c with Z′ = 1) of the previously reported triclinic (P-1 with Z′ = 2) form [Gajera et al. (2013). Acta Cryst. E69, o736–o737]. The molecule in the monoclinic polymorph features a central pyrazolyl ring with an N-bound p-tolyl group and a C-bound 1,3-benzodioxolyl fused-ring system on either side of the C atom bearing the amino group. The dihedral angles between the central ring and the N- and C-bound rings are 50.06 (5) and 27.27 (5)°, respectively. The angle between the pendent rings is 77.31 (4)°, indicating the molecule has a twisted conformation. The five-membered dioxolyl ring has an envelope conformation with the methylene C atom being the flap. The relative disposition of the amino and dioxolyl substituents is syn. One of the independent molecules in the triclinic form has a similar syn disposition but the other has an anti arrangement of these substituents. In the crystal structure of the monoclinic form, molecules assemble into supramolecular helical chains via amino–pyrazolyl N—H...N hydrogen bonds. These are linked into layers via C—H...π interactions, and layers stack along the a axis with no specific interactions between them.http://scripts.iucr.org/cgi-bin/paper?S2056989015016023crystal structureaminepolymorphconformationHirshfeld surface |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mukesh M. Jotani Nilesh N. Gajera Mukesh C. Patel Herman H. Y. Sung Edward R. T. Tiekink |
spellingShingle |
Mukesh M. Jotani Nilesh N. Gajera Mukesh C. Patel Herman H. Y. Sung Edward R. T. Tiekink A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine Acta Crystallographica Section E: Crystallographic Communications crystal structure amine polymorph conformation Hirshfeld surface |
author_facet |
Mukesh M. Jotani Nilesh N. Gajera Mukesh C. Patel Herman H. Y. Sung Edward R. T. Tiekink |
author_sort |
Mukesh M. Jotani |
title |
A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine |
title_short |
A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine |
title_full |
A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine |
title_fullStr |
A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine |
title_full_unstemmed |
A monoclinic polymorph of 4-(2H-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1H-pyrazol-5-amine |
title_sort |
monoclinic polymorph of 4-(2h-1,3-benzodioxol-5-yl)-1-(4-methylphenyl)-1h-pyrazol-5-amine |
publisher |
International Union of Crystallography |
series |
Acta Crystallographica Section E: Crystallographic Communications |
issn |
2056-9890 |
publishDate |
2015-10-01 |
description |
The title compound, C17H15N3O2, is a monoclinic polymorph (P21/c with Z′ = 1) of the previously reported triclinic (P-1 with Z′ = 2) form [Gajera et al. (2013). Acta Cryst. E69, o736–o737]. The molecule in the monoclinic polymorph features a central pyrazolyl ring with an N-bound p-tolyl group and a C-bound 1,3-benzodioxolyl fused-ring system on either side of the C atom bearing the amino group. The dihedral angles between the central ring and the N- and C-bound rings are 50.06 (5) and 27.27 (5)°, respectively. The angle between the pendent rings is 77.31 (4)°, indicating the molecule has a twisted conformation. The five-membered dioxolyl ring has an envelope conformation with the methylene C atom being the flap. The relative disposition of the amino and dioxolyl substituents is syn. One of the independent molecules in the triclinic form has a similar syn disposition but the other has an anti arrangement of these substituents. In the crystal structure of the monoclinic form, molecules assemble into supramolecular helical chains via amino–pyrazolyl N—H...N hydrogen bonds. These are linked into layers via C—H...π interactions, and layers stack along the a axis with no specific interactions between them. |
topic |
crystal structure amine polymorph conformation Hirshfeld surface |
url |
http://scripts.iucr.org/cgi-bin/paper?S2056989015016023 |
work_keys_str_mv |
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