The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study

Objective: This prospective pilot study aims to validate feasibility, efficacy and safeness of the innovative technique of video endoscopy inguinal lymphadenectomy (VEIL) and compare it to open inguinal lymphadenectomy (OIL) in the staging and treatment of vulvar cancer (VC). Material and methods: A...

Full description

Bibliographic Details
Main Authors: Angelica Naldini, Cristiano Rossitto, Fabio Pacelli, Giuseppe Vizzielli, Giuseppe Campagna, Maria Cristina Moruzzi, Giovanni Scambia
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455917300736
id doaj-404a750b4f4b4beca7871d67f42b4ab4
record_format Article
spelling doaj-404a750b4f4b4beca7871d67f42b4ab42020-11-24T22:53:39ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592017-06-0156328128510.1016/j.tjog.2017.04.003The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot studyAngelica Naldini0Cristiano Rossitto1Fabio Pacelli2Giuseppe Vizzielli3Giuseppe Campagna4Maria Cristina Moruzzi5Giovanni Scambia6Division of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyDivision of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyDepartment of Oncology Unit, Catholic University of the Sacred Heart, Campobasso, ItalyDivision of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyDivision of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyDivision of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyDivision of Gynecologic Oncology, Department of Women's and Children's Health, “Agostino Gemelli” Foundation University Hospital, Rome, ItalyObjective: This prospective pilot study aims to validate feasibility, efficacy and safeness of the innovative technique of video endoscopy inguinal lymphadenectomy (VEIL) and compare it to open inguinal lymphadenectomy (OIL) in the staging and treatment of vulvar cancer (VC). Material and methods: All patients affected by VC suitable for bilateral inguinal-femoral lymphadenectomy were prospectively enrolled and submitted to VEIL on one side and OIL contralaterally, sparing the saphenous vein. The surgical and post-surgical data were collected. Univariate analysis included chi square analysis or Fisher's exact test, when appropriate for categorical variables, and the Student t test and Mann–Whitney test when appropriate for continuous variables. Results: Between October 2014 and June 2015 fifteen patients were valuable for the study. Although nodal retrieval was comparable for both procedures, operative time was higher after VEIL. No intraoperative complications were observed in both techniques. Postoperative complications were observed in 3 and 2 cases for OIL and VEIL respectively. One patient needed reoperation after OIL for wound necrosis and infection. According to Campisi's stage, lymphedema resulted significantly to be lower after VEIL (p = 0.024). Conclusions: Waiting for larger series and longer follow-up data, the VEIL seems to be feasible allowing a radical removal of inguinal lymph nodes as well as OIL with lower morbidity.http://www.sciencedirect.com/science/article/pii/S1028455917300736Vulvar cancerVideo endoscopy inguinal lymphadenectomyVEIL
collection DOAJ
language English
format Article
sources DOAJ
author Angelica Naldini
Cristiano Rossitto
Fabio Pacelli
Giuseppe Vizzielli
Giuseppe Campagna
Maria Cristina Moruzzi
Giovanni Scambia
spellingShingle Angelica Naldini
Cristiano Rossitto
Fabio Pacelli
Giuseppe Vizzielli
Giuseppe Campagna
Maria Cristina Moruzzi
Giovanni Scambia
The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
Taiwanese Journal of Obstetrics & Gynecology
Vulvar cancer
Video endoscopy inguinal lymphadenectomy
VEIL
author_facet Angelica Naldini
Cristiano Rossitto
Fabio Pacelli
Giuseppe Vizzielli
Giuseppe Campagna
Maria Cristina Moruzzi
Giovanni Scambia
author_sort Angelica Naldini
title The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
title_short The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
title_full The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
title_fullStr The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
title_full_unstemmed The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
title_sort video endoscopy inguinal lymphadenectomy for vulvar cancer: a pilot study
publisher Elsevier
series Taiwanese Journal of Obstetrics & Gynecology
issn 1028-4559
publishDate 2017-06-01
description Objective: This prospective pilot study aims to validate feasibility, efficacy and safeness of the innovative technique of video endoscopy inguinal lymphadenectomy (VEIL) and compare it to open inguinal lymphadenectomy (OIL) in the staging and treatment of vulvar cancer (VC). Material and methods: All patients affected by VC suitable for bilateral inguinal-femoral lymphadenectomy were prospectively enrolled and submitted to VEIL on one side and OIL contralaterally, sparing the saphenous vein. The surgical and post-surgical data were collected. Univariate analysis included chi square analysis or Fisher's exact test, when appropriate for categorical variables, and the Student t test and Mann–Whitney test when appropriate for continuous variables. Results: Between October 2014 and June 2015 fifteen patients were valuable for the study. Although nodal retrieval was comparable for both procedures, operative time was higher after VEIL. No intraoperative complications were observed in both techniques. Postoperative complications were observed in 3 and 2 cases for OIL and VEIL respectively. One patient needed reoperation after OIL for wound necrosis and infection. According to Campisi's stage, lymphedema resulted significantly to be lower after VEIL (p = 0.024). Conclusions: Waiting for larger series and longer follow-up data, the VEIL seems to be feasible allowing a radical removal of inguinal lymph nodes as well as OIL with lower morbidity.
topic Vulvar cancer
Video endoscopy inguinal lymphadenectomy
VEIL
url http://www.sciencedirect.com/science/article/pii/S1028455917300736
work_keys_str_mv AT angelicanaldini thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT cristianorossitto thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT fabiopacelli thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giuseppevizzielli thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giuseppecampagna thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT mariacristinamoruzzi thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giovanniscambia thevideoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT angelicanaldini videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT cristianorossitto videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT fabiopacelli videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giuseppevizzielli videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giuseppecampagna videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT mariacristinamoruzzi videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
AT giovanniscambia videoendoscopyinguinallymphadenectomyforvulvarcancerapilotstudy
_version_ 1725662582102032384