Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

Choroidal neovascularization (CNV) is the common pathological basis of irreversible visual impairment encountered in a variety of chorioretinal diseases; the pathogenesis of its development is complicated and still imperfectly understood. Recent studies indicated that delta-like ligand 4 (Dll4), one...

Full description

Bibliographic Details
Main Authors: Xiao Dong, Yu-Sheng Wang, Guo-Rui Dou, Hui-Yuan Hou, Yuan-Yuan Shi, Rui Zhang, Ke Ma, Lin Wu, Li-Bo Yao, Yan Cai, Jian Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21526177/pdf/?tool=EBI