Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer

Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer

Secondary bile acids (BAs) and short chain fatty acids (SCFAs), two major types of bacterial metabolites in the colon, cause opposing effects on colonic inflammation at chronically high physiological levels. Primary BAs play critical roles in cholesterol metabolism, lipid digestion, and host&nda...

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Bibliographic Details
Main Authors: Huawei Zeng, Shahid Umar, Bret Rust, Darina Lazarova, Michael Bordonaro
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
bile acids
butyrate
colon cancer
microbiome
inflammation
obesity
Online Access:http://www.mdpi.com/1422-0067/20/5/1214

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