Proregenerative Properties of ECM Molecules

Proregenerative Properties of ECM Molecules

After traumatic injuries to the nervous system, regrowing axons encounter a complex microenvironment where mechanisms that promote regeneration compete with inhibitory processes. Sprouting and axonal regrowth are key components of functional recovery but are often counteracted by inhibitory molecule...

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Main Author: Stefan Plantman
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/981695
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spelling doaj-40578f1807e8410787e2ad20867608362020-11-24T23:13:55ZengHindawi LimitedBioMed Research International2314-61332314-61412013-01-01201310.1155/2013/981695981695Proregenerative Properties of ECM MoleculesStefan Plantman0Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, SwedenAfter traumatic injuries to the nervous system, regrowing axons encounter a complex microenvironment where mechanisms that promote regeneration compete with inhibitory processes. Sprouting and axonal regrowth are key components of functional recovery but are often counteracted by inhibitory molecules. This review covers extracellular matrix molecules that support neuron axonal outgrowth.http://dx.doi.org/10.1155/2013/981695
collection DOAJ
language English
format Article
sources DOAJ
author Stefan Plantman
spellingShingle Stefan Plantman
Proregenerative Properties of ECM Molecules
BioMed Research International
author_facet Stefan Plantman
author_sort Stefan Plantman
title Proregenerative Properties of ECM Molecules
title_short Proregenerative Properties of ECM Molecules
title_full Proregenerative Properties of ECM Molecules
title_fullStr Proregenerative Properties of ECM Molecules
title_full_unstemmed Proregenerative Properties of ECM Molecules
title_sort proregenerative properties of ecm molecules
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2013-01-01
description After traumatic injuries to the nervous system, regrowing axons encounter a complex microenvironment where mechanisms that promote regeneration compete with inhibitory processes. Sprouting and axonal regrowth are key components of functional recovery but are often counteracted by inhibitory molecules. This review covers extracellular matrix molecules that support neuron axonal outgrowth.
url http://dx.doi.org/10.1155/2013/981695
work_keys_str_mv AT stefanplantman proregenerativepropertiesofecmmolecules
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