Automatic construction of metabolic models with enzyme constraints

Abstract Background In order to improve the accuracy of constraint-based metabolic models, several approaches have been developed which intend to integrate additional biological information. Two of these methods, MOMENT and GECKO, incorporate enzymatic (kcat) parameters and enzyme mass constraints t...

Full description

Bibliographic Details
Main Authors: Pavlos Stephanos Bekiaris, Steffen Klamt
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3329-9

Similar Items