VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans.
Neuritogenesis is a critical early step in the development and maturation of neurons and neuronal circuits. While extracellular directional cues are known to specify the site and orientation of nascent neurite formation in vivo, little is known about the genetic pathways that block inappropriate neu...
Main Authors: | Leticia Sanchez-Alvarez, Jiravat Visanuvimol, Andrea McEwan, Anna Su, Janice H Imai, Antonio Colavita |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3164692?pdf=render |
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