Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases

Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases

Introduction: Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) gained increasing attention regarding tumorprogression and metastatic spread in breast cancer. The aim of this study was to examine ALCAM expression levels in primary breast cancer and distant metastases of the same patient withi...

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Main Authors: M. Ihnen, N. Köhler, J. F. Kersten, K. Milde-Langosch, K. Beck, S. Höller, V. Müller, I. Witzel, F. Jänicke, E. Kilic
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2010-0685
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spelling doaj-408712fe320541868134341a54fb2a2d2020-11-24T22:34:59ZengHindawi LimitedDisease Markers0278-02401875-86302010-01-01282717810.3233/DMA-2010-0685Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer MetastasesM. Ihnen0N. Köhler1J. F. Kersten2K. Milde-Langosch3K. Beck4S. Höller5V. Müller6I. Witzel7F. Jänicke8E. Kilic9Department of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Statistics and Epidemiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyInstitute for Pathology, University Hospital of Basel, Schönbeinstrasse 40, 4031 Basel, SwitzerlandDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, GermanyInstitute for Pathology, University Hospital of Basel, Schönbeinstrasse 40, 4031 Basel, SwitzerlandIntroduction: Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) gained increasing attention regarding tumorprogression and metastatic spread in breast cancer. The aim of this study was to examine ALCAM expression levels in primary breast cancer and distant metastases of the same patient within 29 autopsy cases to better understand the underlying mechanisms of metastases and the role of adhesion molecules in this process.http://dx.doi.org/10.3233/DMA-2010-0685
collection DOAJ
language English
format Article
sources DOAJ
author M. Ihnen
N. Köhler
J. F. Kersten
K. Milde-Langosch
K. Beck
S. Höller
V. Müller
I. Witzel
F. Jänicke
E. Kilic
spellingShingle M. Ihnen
N. Köhler
J. F. Kersten
K. Milde-Langosch
K. Beck
S. Höller
V. Müller
I. Witzel
F. Jänicke
E. Kilic
Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
Disease Markers
author_facet M. Ihnen
N. Köhler
J. F. Kersten
K. Milde-Langosch
K. Beck
S. Höller
V. Müller
I. Witzel
F. Jänicke
E. Kilic
author_sort M. Ihnen
title Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
title_short Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
title_full Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
title_fullStr Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
title_full_unstemmed Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
title_sort expression levels of activated leukocyte cell adhesion molecule (alcam/cd166) in primary breast carcinoma and distant breast cancer metastases
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2010-01-01
description Introduction: Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) gained increasing attention regarding tumorprogression and metastatic spread in breast cancer. The aim of this study was to examine ALCAM expression levels in primary breast cancer and distant metastases of the same patient within 29 autopsy cases to better understand the underlying mechanisms of metastases and the role of adhesion molecules in this process.
url http://dx.doi.org/10.3233/DMA-2010-0685
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