LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer
Current understanding of aggressive human basal-like triple-negative breast cancer (TNBC) remains incomplete. In this study, we show endothelial lipase (LIPG) is aberrantly overexpressed in basal-like TNBCs. We demonstrate that LIPG is required for in vivo tumorigenicity and metastasis of TNBC cells...
Main Authors: | Pang-Kuo Lo, Yuan Yao, Ji Shin Lee, Yongshu Zhang, Weiliang Huang, Maureen A Kane, Qun Zhou |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/31334 |
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