On the Morphology of the Drosophila Heart
The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few e...
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doaj-40ab4d0225b7475c8de2fb26e38a3c442020-11-25T00:08:47ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252016-04-01321510.3390/jcdd3020015jcdd3020015On the Morphology of the Drosophila HeartBarbara Rotstein0Achim Paululat1Department of Zoology/Developmental Biology, University of Osnabrück, Osnabrück 49069, GermanyDepartment of Zoology/Developmental Biology, University of Osnabrück, Osnabrück 49069, GermanyThe circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the Drosophila heart has also attracted the attention of researchers in the field of biomedicine. This development is mainly due to the fact that several genes causing human heart disease are also present in Drosophila, where they play the same or similar roles in heart development, maintenance or physiology as their respective counterparts in humans. This review will attempt to briefly introduce the anatomy of the Drosophila circulatory system and then focus on the different cell types and non-cellular tissue that constitute the heart.http://www.mdpi.com/2308-3425/3/2/15Drosophila melanogastercardiovascular systemheartdorsal vesselcirculatory system |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Barbara Rotstein Achim Paululat |
spellingShingle |
Barbara Rotstein Achim Paululat On the Morphology of the Drosophila Heart Journal of Cardiovascular Development and Disease Drosophila melanogaster cardiovascular system heart dorsal vessel circulatory system |
author_facet |
Barbara Rotstein Achim Paululat |
author_sort |
Barbara Rotstein |
title |
On the Morphology of the Drosophila Heart |
title_short |
On the Morphology of the Drosophila Heart |
title_full |
On the Morphology of the Drosophila Heart |
title_fullStr |
On the Morphology of the Drosophila Heart |
title_full_unstemmed |
On the Morphology of the Drosophila Heart |
title_sort |
on the morphology of the drosophila heart |
publisher |
MDPI AG |
series |
Journal of Cardiovascular Development and Disease |
issn |
2308-3425 |
publishDate |
2016-04-01 |
description |
The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the Drosophila heart has also attracted the attention of researchers in the field of biomedicine. This development is mainly due to the fact that several genes causing human heart disease are also present in Drosophila, where they play the same or similar roles in heart development, maintenance or physiology as their respective counterparts in humans. This review will attempt to briefly introduce the anatomy of the Drosophila circulatory system and then focus on the different cell types and non-cellular tissue that constitute the heart. |
topic |
Drosophila melanogaster cardiovascular system heart dorsal vessel circulatory system |
url |
http://www.mdpi.com/2308-3425/3/2/15 |
work_keys_str_mv |
AT barbararotstein onthemorphologyofthedrosophilaheart AT achimpaululat onthemorphologyofthedrosophilaheart |
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1725414588520857600 |