Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

Today, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, becaus...

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Main Authors: Saji Uthaman, Sang Joon Lee, Kondareddy Cherukula, Chong-Su Cho, In-Kyu Park
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/959175
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spelling doaj-40cf34e9a20e44baa286b3f21337cc502020-11-24T22:49:43ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/959175959175Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene TherapySaji Uthaman0Sang Joon Lee1Kondareddy Cherukula2Chong-Su Cho3In-Kyu Park4Department of Biomedical Science and BK21 PLUS Centre for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 501-746, Republic of KoreaDepartment of Biomedical Science and BK21 PLUS Centre for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 501-746, Republic of KoreaDepartment of Biomedical Science and BK21 PLUS Centre for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 501-746, Republic of KoreaDepartment of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of KoreaDepartment of Biomedical Science and BK21 PLUS Centre for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 501-746, Republic of KoreaToday, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, because of their imaging characteristics and therapeutic properties such as drug and gene carriers. Polymer-coated magnetic particles are currently of particular interest to investigators in the fields of nanobiomedicine and fundamental biomaterials. Theranostic magnetic nanoparticles that are encapsulated or coated with polymers not only exhibit imaging properties in response to stimuli, but also can efficiently deliver various drugs and therapeutic genes. Even though a large number of polymer-coated magnetic nanoparticles have been fabricated over the last decade, most of these have only been used for imaging purposes. The focus of this review is on polysaccharide-coated magnetic nanoparticles used for imaging and gene delivery.http://dx.doi.org/10.1155/2015/959175
collection DOAJ
language English
format Article
sources DOAJ
author Saji Uthaman
Sang Joon Lee
Kondareddy Cherukula
Chong-Su Cho
In-Kyu Park
spellingShingle Saji Uthaman
Sang Joon Lee
Kondareddy Cherukula
Chong-Su Cho
In-Kyu Park
Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
BioMed Research International
author_facet Saji Uthaman
Sang Joon Lee
Kondareddy Cherukula
Chong-Su Cho
In-Kyu Park
author_sort Saji Uthaman
title Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
title_short Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
title_full Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
title_fullStr Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
title_full_unstemmed Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
title_sort polysaccharide-coated magnetic nanoparticles for imaging and gene therapy
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Today, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, because of their imaging characteristics and therapeutic properties such as drug and gene carriers. Polymer-coated magnetic particles are currently of particular interest to investigators in the fields of nanobiomedicine and fundamental biomaterials. Theranostic magnetic nanoparticles that are encapsulated or coated with polymers not only exhibit imaging properties in response to stimuli, but also can efficiently deliver various drugs and therapeutic genes. Even though a large number of polymer-coated magnetic nanoparticles have been fabricated over the last decade, most of these have only been used for imaging purposes. The focus of this review is on polysaccharide-coated magnetic nanoparticles used for imaging and gene delivery.
url http://dx.doi.org/10.1155/2015/959175
work_keys_str_mv AT sajiuthaman polysaccharidecoatedmagneticnanoparticlesforimagingandgenetherapy
AT sangjoonlee polysaccharidecoatedmagneticnanoparticlesforimagingandgenetherapy
AT kondareddycherukula polysaccharidecoatedmagneticnanoparticlesforimagingandgenetherapy
AT chongsucho polysaccharidecoatedmagneticnanoparticlesforimagingandgenetherapy
AT inkyupark polysaccharidecoatedmagneticnanoparticlesforimagingandgenetherapy
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