Change in DNA methylation patterns of SLC6A4 gene in the gastric mucosa in functional dyspepsia.

Change in DNA methylation patterns of SLC6A4 gene in the gastric mucosa in functional dyspepsia.

BACKGROUND: The neurochemical serotonin (5-HT) is an important signaling molecule in the gastrointestinal motor and sensory functions. A key regulator of 5-HT levels is the transmembrane serotonin transporter (5-HTT; SLC6A4) that governs the reuptake of 5-HT. Recent studies have indicated 5-HTT expr...

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Bibliographic Details
Main Authors: Tomomitsu Tahara, Tomoyuki Shibata, Masaaki Okubo, Kazuya Sumi, Takamitsu Ishizuka, Masakatsu Nakamura, Mitsuo Nagasaka, Yoshihito Nakagawa, Naoki Ohmiya, Tomiyasu Arisawa, Ichiro Hirata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4141787?pdf=render

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http://europepmc.org/articles/PMC4141787?pdf=render

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