Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

• Main Authors: Marcelo Lorenzi Marques, Gabriel Salum D'Alessandro, Daher Cezar Chade, Valéria Pereira Lanzoni, Samuel Saiovici, Cláudio José Ramos de Almeida
• Format: Article
• Language: English
• Published: Associação Paulista de Medicina
• Series: São Paulo Medical Journal
• Subjects: Urinary bladder; Urinary bladder neoplasms; Mucinous adenocarcinoma; Immunohistochemistry; Signet ring cell carcinoma
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000500011&lng=en&tlng=en

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.