Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report

Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report

We present the case of an 8-year-old immunocompromised boy with invasive pulmonary aspergillosis, complicated with pleural empyema and disseminated to the bone and central nervous system (CNS). The patient was treated with combined systemic antifungal agents (voriconazole and caspofungin) and intrap...

Full description

Bibliographic Details
Main Authors: Alanoud Almuhareb, Zakaria Habib
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034117301296
id doaj-410a926194dd4063afe3a59f2b1b62c0
record_format Article
spelling doaj-410a926194dd4063afe3a59f2b1b62c02020-11-24T22:39:58ZengElsevierJournal of Infection and Public Health1876-03412018-03-01112280282Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case reportAlanoud Almuhareb0Zakaria Habib1King Faisal Specialist Hospital & Research Centre Pharmaceutical Care Division, Saudi Arabia; Corresponding author at: King Faisal Specialist Hospital & Research Centre Pharmaceutical Care Division, P.O. Box 3354, Riyadh 11211, Saudi Arabia.King Faisal Specialist Hospital & Research Centre Surgery Department, Saudi ArabiaWe present the case of an 8-year-old immunocompromised boy with invasive pulmonary aspergillosis, complicated with pleural empyema and disseminated to the bone and central nervous system (CNS). The patient was treated with combined systemic antifungal agents (voriconazole and caspofungin) and intrapleural instillation of liposomal amphotericin B, in addition to surgical intervention. The treatment was well tolerated and resulted in remarkable clinical and radiological pulmonary improvement. Keywords: Invasive aspergillosis, Pleural empyema, Intrapleural, Amphotericin B, Combined antifungalhttp://www.sciencedirect.com/science/article/pii/S1876034117301296
collection DOAJ
language English
format Article
sources DOAJ
author Alanoud Almuhareb
Zakaria Habib
spellingShingle Alanoud Almuhareb
Zakaria Habib
Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
Journal of Infection and Public Health
author_facet Alanoud Almuhareb
Zakaria Habib
author_sort Alanoud Almuhareb
title Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
title_short Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
title_full Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
title_fullStr Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
title_full_unstemmed Management of Aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: Case report
title_sort management of aspergillus pleural empyema with combined systemic and intrapleural antifungal therapy in a pediatric patient: case report
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2018-03-01
description We present the case of an 8-year-old immunocompromised boy with invasive pulmonary aspergillosis, complicated with pleural empyema and disseminated to the bone and central nervous system (CNS). The patient was treated with combined systemic antifungal agents (voriconazole and caspofungin) and intrapleural instillation of liposomal amphotericin B, in addition to surgical intervention. The treatment was well tolerated and resulted in remarkable clinical and radiological pulmonary improvement. Keywords: Invasive aspergillosis, Pleural empyema, Intrapleural, Amphotericin B, Combined antifungal
url http://www.sciencedirect.com/science/article/pii/S1876034117301296
work_keys_str_mv AT alanoudalmuhareb managementofaspergilluspleuralempyemawithcombinedsystemicandintrapleuralantifungaltherapyinapediatricpatientcasereport
AT zakariahabib managementofaspergilluspleuralempyemawithcombinedsystemicandintrapleuralantifungaltherapyinapediatricpatientcasereport
_version_ 1725706639858728960

Similar Items