Delivery of targeted gene therapies using a hybrid cryogel-coated prosthetic vascular graft

Delivery of targeted gene therapies using a hybrid cryogel-coated prosthetic vascular graft

Objectives The success of prosthetic vascular grafts in the management of peripheral arterial disease is frequently limited by the development of anastomotic neointimal hyperplasia (ANIH), with the host response to prosthetic grafts beginning soon after implantation. To address this, we combine a pl...

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Bibliographic Details
Main Authors: Cindy Huynh, Ting-Yu Shih, Alexander Mammoo, Amruta Samant, Saif Pathan, David W. Nelson, Christiane Ferran, David Mooney, Frank LoGerfo, Leena Pradhan-Nabzdyk
Format: Article
Language:English
Published: PeerJ Inc. 2019-08-01
Series:PeerJ
Subjects:
Vascular surgery
Peripheral arterial disease
Prosthetic graft material
Intimal hyperplasia
Biomaterials
Cryogel
Online Access:https://peerj.com/articles/7377.pdf

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