Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene

Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene

Abstract Background Genome-wide association studies (GWAS) have identified hundreds of loci associated with coronary artery disease (CAD) and blood pressure (BP) or hypertension. Many of these loci are not linked to traditional risk factors, nor do they include obvious candidate genes, complicating...

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Main Authors: Simon Lalonde, Valérie-Anne Codina-Fauteux, Sébastian Méric de Bellefon, Francis Leblanc, Mélissa Beaudoin, Marie-Michelle Simon, Rola Dali, Tony Kwan, Ken Sin Lo, Tomi Pastinen, Guillaume Lettre
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Genome Biology
Subjects:
Vascular endothelium
Endothelial dysfunction
Coronary artery disease
Blood pressure
Hypertension
Genome-wide association study
Online Access:http://link.springer.com/article/10.1186/s13059-019-1749-5

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