Research progress on pharmacological effect of Salvianolic acid for injection in post-stroke depression
Post-stroke depression (PSD) is one of the most common affective disorders after acute cerebrovascular injury. It significantly increases the mortality, disability rate and recurrence rate of stroke, which places a heavy burden on families and society. The etiology of PSD is not yet clear, involv...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2020-05-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/202010/14.pdf |
| Summary: | Post-stroke depression (PSD) is one of the most common affective disorders after acute
cerebrovascular injury. It significantly increases the mortality, disability rate and recurrence
rate of stroke, which places a heavy burden on families and society. The etiology of PSD is
not yet clear, involving a series of complex mechanisms. Inflammatory response, apoptosis,
neurotrophic factors, neurotransmitters and many others may play important roles, and there
is no effective treatment. Salvianolic acid for injection (SAFI) has the functions of antiinflammatory,
anti-oxidative stress, anti-apoptotic and can improve depressive behavior. It is
expected to become a new antidepressant for the treatment of PSD. |
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| ISSN: | 1007-1237 1007-1237 |