Computer-Aided Drug Repurposing: A Cyclooxygenase-2 Inhibitor Celecoxib as a Ligand for Estrogen Receptor Alpha

Computer-Aided Drug Repurposing: A Cyclooxygenase-2 Inhibitor Celecoxib as a Ligand for Estrogen Receptor Alpha

A cyclooxygenase-2 (COX-2) inhibitor celecoxib has been previously reported to have cytotoxic activities towards gastric, prostate, ovarian, colon and breast cancer cell lines. This article reports that the cytotoxic activities of celecoxib could be resulted from its activity as a potent ligand for...

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Bibliographic Details
Main Authors: Enade Perdana Istyastono, Florentinus Dika Octa Riswanto, Sri Hartati Yuliani
Format: Article
Language:English
Published: Universitas Gadjah Mada 2015-11-01
Series:Indonesian Journal of Chemistry
Subjects:
cyclooxygenase-2
estrogen receptor alpha
molecular docking
celecoxib
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/21196

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